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| 名称： | anti- XRCC5/Ku80 antibody |
|---|---|
| 货号： | FNab09555 |
| 适应种属： | 人源 |
| 规格： | 100ug(微克) |
| 状态： | 液体 |
| 纯化方法： | 免疫亲和纯化 |
| 纯度： | 经SDS-PAGE分析,纯度大于95% |
| 宿主： | 兔 |
| 亚型： | lgG |
| 存储： | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月（避免反复冻融） |
| 免疫原： | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
| 免疫原别称： | 86 kDa subunit of Ku antigen antibody, CTC85 antibody, CTCBF antibody, DNA repair protein XRCC5 antibody, FLJ39089 antibody, G22P2 antibody, KARP 1 antibody, KARP1 antibody, Ku80 antibody, Ku86 antibody, KUB2 antibody, NFIV antibody, Nuclear fac |
| 分子量： | Refer to figures |
| 验证应用： | ELISA, WB, IHC |
| 建议稀释比例： | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| UniProt ID： | P13010 |
| 克隆性： | 多克隆 |
| 背景介绍： | The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |
| 图像： |  Immunohistochemistry of paraffin-embedded human colon cancer using FNab09555(XRCC5 antibody) at dilution of 1:100。
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