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产品详情
| 名称： | anti- Chk1 antibody |
|---|---|
| 货号： | FNab01653 |
| 适应种属： | 人源,大鼠,小鼠 |
| 规格： | 100ug(微克) |
| 状态： | 液体 |
| 纯化方法： | 蛋白A/G柱纯化 |
| 纯度： | 经SDS-PAGE分析,纯度大于95% |
| 宿主： | 小鼠 |
| 亚型： | IgG2a |
| 存储： | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月（避免反复冻融） |
| 免疫原： | CHK1 checkpoint homolog |
| 免疫原别称： | CHEK1 antibody, Chk1 antibody |
| 分子量： | 50 kDa |
| 验证应用： | ELISA, WB, IHC |
| 建议稀释比例： | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| UniProt ID： | O14757 |
| 克隆性： | 单克隆 |
| 背景介绍： | HEK1(Checkpoint kinase-1) is also named as CHK1 and belongs to the protein kinase superfamily. It is implicated in a circuit in which it activates checkpoints, DNA repair and proliferating cell nuclear antigen and FANCD2 monoubiquitinylation(PMID:21389083). CHEK1 protects vertebrate cells against spontaneous chromosome missegregation and is required to sustain anaphase delay when spindle function is disrupted by taxol(PMID:17276342). It has 3 isoforms produced by alternative splicing with the molecular mass of 54 kDa, 44 kDa and 50 kDa. |
| 图像： |  Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab01653(CHK1 Antibody) at dilution of 1:50。
|
