服务热线
18062437365
名称: | anti- RPS3 antibody |
---|---|
货号: | FNab07475 |
适应种属: | 人源,大鼠,小鼠 |
规格: | 100ug(微克) |
状态: | 液体 |
纯化方法: | 免疫亲和纯化 |
纯度: | 经SDS-PAGE分析,纯度大于95% |
宿主: | 兔 |
亚型: | lgG |
存储: | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月(避免反复冻融) |
免疫原: | ribosomal protein S3 |
分子量: | 27 kDa |
验证应用: | ELISA, WB, IHC |
建议稀释比例: | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
UniProt ID: | P23396 |
克隆性: | 多克隆 |
背景介绍: | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively. As is typical for |
图像: | Immunohistochemistry of paraffin-embedded human ovary tumor using FNab07475(RPS3 antibody) at dilution of 1:50。 mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab07475(RPS3 antibody) at dilution of 1:1000。 |