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产品详情
| 名称： | anti- TSG101 antibody |
|---|---|
| 货号： | FNab09040 |
| 适应种属： | 人源,大鼠,小鼠 |
| 规格： | 100ug(微克) |
| 状态： | 液体 |
| 纯化方法： | 免疫亲和纯化 |
| 纯度： | 经SDS-PAGE分析,纯度大于95% |
| 宿主： | 兔 |
| 亚型： | lgG |
| 存储： | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月（避免反复冻融） |
| 免疫原： | tumor susceptibility gene 101 |
| 免疫原别称： | ESCRT I complex subunit TSG101 antibody, TSG10 antibody, TSG101 antibody, tumor susceptibility gene 101 antibody, VPS23 antibody |
| 分子量： | 44 kDa |
| 验证应用： | ELISA, WB, IHC |
| 建议稀释比例： | WB: 1:500 - 1:2000; IHC: 1:50 - 1:100 |
| UniProt ID： | Q99816 |
| 克隆性： | 多克隆 |
| 背景介绍： | The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. |
| 图像： |  Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab09040( TSG101 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9)。
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