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发布时间：2023-10-13 11:24 咨询量：
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产品详情
| 名称： | anti- RAB7A antibody |
|---|---|
| 货号： | FNab07043 |
| 适应种属： | 人源,大鼠,小鼠 |
| 规格： | 100ug(微克) |
| 状态： | 液体 |
| 纯化方法： | 免疫亲和纯化 |
| 纯度： | 经SDS-PAGE分析,纯度大于95% |
| 宿主： | 兔 |
| 亚型： | lgG |
| 存储： | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月（避免反复冻融） |
| 免疫原： | RAB7A, member RAS oncogene family |
| 免疫原别称： | PRO2706 antibody, RAB7 antibody, RAB7A antibody, Ras related protein Rab 7a antibody |
| 分子量： | 23 kDa |
| 验证应用： | ELISA, WB, IHC |
| 建议稀释比例： | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| UniProt ID： | P51149 |
| 克隆性： | 多克隆 |
| 背景介绍： | Key regulator in endo-lysosomal trafficking. Governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades. Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth-factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism. Also involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes, pathogen-induced phagosomes(or vacuoles) and autophagosomes. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes. Plays important roles in microbial pathogen infection and survival, as well as in participating in the li |
| 图像： |  Immunohistochemistry of paraffin-embedded human stomach tissue slide using FNab07043(RAB7A Antibody) at dilution of 1:50。
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