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| 名称： | anti- CD68 antibody |
|---|---|
| 货号： | FNab01491 |
| 适应种属： | 人源,小鼠 |
| 规格： | 100ug(微克) |
| 状态： | 液体 |
| 纯化方法： | 免疫亲和纯化 |
| 纯度： | 经SDS-PAGE分析,纯度大于95% |
| 宿主： | 兔 |
| 亚型： | lgG |
| 存储： | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月（避免反复冻融） |
| 免疫原： | CD68 molecule |
| 免疫原别称： | CD68 antibody, CD68 molecule antibody, DKFZp686M18236 antibody, GP110 antibody, Macrosialin antibody, SCARD1 antibody |
| 分子量： | Refer to figures |
| 验证应用： | ELISA, IHC, WB |
| 建议稀释比例： | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| UniProt ID： | P34810 |
| 克隆性： | 多克隆 |
| 背景介绍： | This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. |
| 图像： |  Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01491( CD68 Antibody) at dilution of 1:50。  Mouse spleen tissue were subjected to SDS PAGE followed by western blot with FNab01491 (CD68 Antibody) at dilution of 1:1000。 |
